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1

Microarrays and toxicology: The advent of toxicogenomics

Emile F. Nuwaysir, Michael Bittner, Jeffrey Trent, J. Carl Barrett, Cynthia A. Afshari

Journal:

Molecular Carcinogenesis

Year:

1999

Language:

english

File:

PDF, 172 KB

english, 1999

2

Estrogen upregulation of BRCA1 expression with no effect on localization

Donato Romagnolo, Lois A. Annab, Tracy E. Thompson, John I. Risinger, Lori A. Terry, J. Carl Barrett, Cynthia A. Afshari

Journal:

Molecular Carcinogenesis

Year:

1998

Language:

english

File:

PDF, 168 KB

english, 1998

3

Discovery in toxicology: Mediation by gene expression array technology

Hisham K. Hamadeh, Pierre Bushel, Richard Paules, Cynthia A. Afshari

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2001

Language:

english

File:

PDF, 1.25 MB

english, 2001

4

Novel consensus DNA-binding sequence for BRCA1 protein complexes

P. LouAnn Cable, Cindy A. Wilson, Frank J. Calzone, Frank J. Rauscher III, Ralph Scully, David M. Livingston, Leping Li, Courtney B. Blackwell, P. Andrew Futreal, Cynthia A. Afshari

Journal:

Molecular Carcinogenesis

Year:

2003

Language:

english

File:

PDF, 257 KB

english, 2003

5

Negative regulation of mitogen-stimulated, anchorage-independent cell growth by a tumor-suppressor gene function

Cynthia A. Afshari, J. Carl Barrett

Journal:

Molecular Carcinogenesis

Year:

1993

Language:

english

File:

PDF, 843 KB

english, 1993

6

Genomic interrogation of mechanism(s) underlying cellular responses to toxicants

Rupesh P Amin, Hisham K Hamadeh, Pierre R Bushel, Lee Bennett, Cynthia A Afshari, Richard S Paules

Journal:

Year:

2002

Language:

english

File:

PDF, 217 KB

english, 2002

7

Combination of functional genomics approaches and microarray analyses to define candidate senescence genes

Annab, Lois, Kouprina, Natalay, Larionov, Vladimir, Vojta, Patrick, Katoh, Motonobu, Bushel, Pierre, Martin, Karla, Oshimura, Mitsuo, Barrett, J. Carl, Afshari, Cynthia

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 28 KB

english, 2001

8

ATM-dependent responses to DNA-damaging agents

Paules, Richard S., Innes, Cynthia L., Sieber, Stella O., Shackelford, Rodney E., Heinloth, Alexandra N., Deming, Paula B., Cistulli, Cheryl A., Bennett, Lee, Bushel, Pierre R., Afshari, Cynthia A.

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 35 KB

english, 2001

9

Deregulation of specific E2F complexes by the v-mos oncogene

Afshari, Cynthia A, Rhodes, Nelson, Paules, Richard S, Mudryj, Maria

Journal:

Year:

1997

Language:

english

File:

PDF, 499 KB

english, 1997

10

Establishment and Characterization of a Breast Cell Strain Containing a BRCA1 185delAG Mutation

Lois A. Annab, Lori Terry, P.LouAnn Cable, Jennifer Brady, Martha R. Stampfer, J.Carl Barrett, Cynthia A. Afshari

Journal:

Gynecologic Oncology

Year:

2000

Language:

english

File:

PDF, 117 KB

english, 2000

11

Loss of Expression and Altered Localization of KAI1 and CD9 Protein Are Associated with Epithelial Ovarian Cancer Progression

Christopher D. Houle, Xiao-Yu Ding, Julie F. Foley, Cynthia A. Afshari, J.Carl Barrett, Barbara J. Davis

Journal:

Gynecologic Oncology

Year:

2002

Language:

english

File:

PDF, 969 KB

english, 2002

12

Integration of clinical and gene expression endpoints to explore furan-mediated hepatotoxicity

Hisham K Hamadeh, Supriya Jayadev, Elias T Gaillard, Qihong Huang, Raymond Stoll, Kerry Blanchard, Jeff Chou, Charles J Tucker, Jennifer Collins, Robert Maronpot, Pierre Bushel, Cynthia A Afshari

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2004

Language:

english

File:

PDF, 492 KB

english, 2004

13

Is Na+ channel the culprit?

Yusheng Qu, Mei Fang, Vince Torti, Dale Stevens, Robert Dunn, Cynthia Afshari, Hugo Vargas

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

14

Computational selection of distinct class- and subclass-specific gene expression signatures

Pierre R. Bushel, Hisham K. Hamadeh, Lee Bennett, James Green, Alan Ableson, Stephen Misener, Cynthia A. Afshari, Richard S. Paules

Journal:

Journal of Biomedical Informatics

Year:

2002

Language:

english

File:

PDF, 406 KB

english, 2002

15

Histologically normal human mammary epithelia with silenced p16INK4a overexpress COX-2, promoting a premalignant program

Yongping G Crawford, Mona L Gauthier, Anita Joubel, Kristin Mantei, Krystyna Kozakiewicz, Cynthia A Afshari, Thea D Tlsty

Journal:

Year:

2004

Language:

english

File:

PDF, 536 KB

english, 2004

16

Investigation of the Role of G1/S Cell Cycle Mediators in Cellular Senescence

Cynthia A. Afshari, Patrick J. Vojta, Lois A. Annab, P.Andrew Futreal, T.Brian Willard, J.Carl Barrett

Journal:

Experimental Cell Research

Year:

1993

File:

PDF, 476 KB

1993

17

Dislocation of the Donor Graft to the Posterior Segment in Descemet Stripping Automated Endothelial Keratoplasty

Natalie A. Afshari, Mark S. Gorovoy, Sonia H. Yoo, Terry Kim, Alan N. Carlson, George O.D. Rosenwasser, Neil B. Griffin, Brooks W. McCuen II, Cynthia A. Toth, Francis W. Price Jr, Marianne Price, Mark

Journal:

American Journal of Ophthalmology

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

18

Cataract formation after initial trabeculectomy in young patients

Ron Afshari Adelman, Stacey C Brauner, Natalie A Afshari, Cynthia L Grosskreutz

Journal:

Year:

2003

Language:

english

File:

PDF, 88 KB

english, 2003

19

Les promesses de la toxicogénomique

Cynthia A. Afshari, Hisham Hamadeh

Journal:

Year:

2000

File:

PDF, 1.01 MB

2000

20

Isolation of a functional copy of the human BRCA1 gene by transformation-associated recombination in yeast

Lois A. Annab, Natalya Kouprina, Greg Solomon, P.Louann Cable, David E. Hill, J.Carl Barrett, Vladimir Larionov, Cynthia A. Afshari

Journal:

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

21

Regulation of p53 stability and activity in response to genotoxic stress

Michael S. Colman, Cynthia A. Afshari, J.Carl Barrett

Journal:

Mutation Research/Reviews in Mutation Research

Year:

2000

Language:

english

File:

PDF, 117 KB

english, 2000

22

Role of a Tumor-Suppressor Gene in the Negative Control of Anchorage-Independent Growth of Syrian Hamster Cells

Minoru Koi, Cynthia A. Afshari, Lois A. Annab and J. Carl Barrett

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.21 MB

english, 1989

23

Functional Copies of a Human Gene can be Directly Isolated by Transformation-Associated Recombination Cloning with a Small 3′end Target Sequence

Natalay Kouprina, Lois Annab, Joan Graves, Cynthia Afshari, J. Carl Barrett, Michael A. Resnick and Vladimir Larionov

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 910 KB

english, 1998

24

Supplement 5: Cell Proliferation and Chemical Carcinogenesis || Cell Cycle Controls: Potential Targets for Chemical Carcinogens?

Cynthia A. Afshari and J. Carl Barrett

Journal:

Environmental Health Perspectives

Year:

1993

Language:

english

File:

PDF, 1.33 MB

english, 1993

25

Toxicogenomics || Identification of Platform-Independent Gene Expression Markers of Cisplatin Nephrotoxicity

Karol L. Thompson, Cynthia A. Afshari, Rupesh P. Amin, Timothy A. Bertram, Bruce Car, Michael Cunningham, Clive Kind, Jeffrey A. Kramer, Michael Lawton, Michael Mirsky, Jorge M. Naciff, Victor Oreffo,

Journal:

Environmental Health Perspectives

Year:

2004

Language:

english

File:

PDF, 1.92 MB

english, 2004

26

Progress in the Application of DNA Microarrays

Edward K. Lobenhofer, Pierre R. Bushel, Cynthia A. Afshari and Hisham K. Hamadeh

Journal:

Environmental Health Perspectives

Year:

2001

Language:

english

File:

PDF, 3.97 MB

english, 2001

27

Current and Future Applications of Toxicogenomics: Results Summary of a Survey from the HESI Genomics State of Science Subcommittee

Syril Pettit, Shelley Ann des Etages, Louis Mylecraine, Ronald Snyder, Jennifer Fostel, Robert T. Dunn II, Kenneth Haymes, Manuel Duval, James Stevens, Cynthia Afshari and Alison Vickers

Journal:

Environmental Health Perspectives

Year:

2010

Language:

english

File:

PDF, 1.62 MB

english, 2010

28

Application of Genomics for Identification of Systemic Toxicity Triggers Associated With VEGF-R Inhibitors

Hamadeh, Hisham K., Todd, Marque, Healy, Laura, Meyer, James T., Kwok, Annie M., Higgins, Marnie, Afshari, Cynthia A.

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

29

Perspective: Microarray Technology, Seeing More Than Spots

Afshari, Cynthia A.

Journal:

Year:

2002

Language:

english

File:

PDF, 232 KB

english, 2002

30

Assessing Gene Significance from cDNA Microarray Expression Data via Mixed Models

Wolfinger, Russell D., Gibson, Greg, Wolfinger, Elizabeth D., Bennett, Lee, Hamadeh, Hisham, Bushel, Pierre, Afshari, Cynthia, Paules, Richard S.

Journal:

Journal of Computational Biology

Year:

2001

Language:

english

File:

PDF, 235 KB

english, 2001

31

Gene Chips and Functional Genomics: A new technology will allow environmental health scientists to track the expression of thousands of genes in a single, fast and easy test

Hisham Hamadeh and Cynthia A. Afshari

Journal:

American Scientist

Year:

2000

Language:

english

File:

PDF, 2.78 MB

english, 2000

32

Current and Future Applications of Toxicogenomics: Results Summary  of a Survey from the HESI Genomics State of Science Subcommittee

Pettit, Syril, des Etages, Shelley Ann, Mylecraine, Louis, Snyder, Ronald, Fostel, Jennifer, Dunn, Robert T., Haymes, Kenneth, Duval, Manuel, Stevens, James, Afshari, Cynthia, Vickers, Alison

Journal:

Environmental Health Perspectives

Year:

2010

Language:

english

File:

PDF, 796 KB

english, 2010

33

Estrogen Receptor-Dependent Genomic Responses in the Uterus Mirror the Biphasic Physiological Response to Estrogen

Hewitt, Sylvia Curtis, Deroo, Bonnie J., Hansen, Katherine, Collins, Jennifer, Grissom, Sherry, Afshari, Cynthia A., Korach, Kenneth S.

Journal:

Molecular Endocrinology

Year:

2003

Language:

english

File:

PDF, 588 KB

english, 2003

34

Regulation of DNA Replication Fork Genes by 17β-Estradiol

Lobenhofer, Edward K., Bennett, Lee, Cable, P. LouAnn, Li, Leping, Bushel, Pierre R., Afshari, Cynthia A.

Journal:

Molecular Endocrinology

Year:

2002

Language:

english

File:

PDF, 568 KB

english, 2002

35

Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats

Taylor, Scott, Ominsky, Michael S., Hu, Rong, Pacheco, Efrain, He, Yudong D., Brown, Danielle L., Aguirre, J. Ignacio, Wronski, Thomas J., Buntich, Sabina, Afshari, Cynthia A., Pyrah, Ian, Nioi, Paul,

Journal:

Year:

2016

Language:

english

File:

PDF, 2.17 MB

english, 2016

36

Prediction of Nephrotoxicant Action and Identification of Candidate Toxicity-Related Biomarkers

Thukral, Sushil, Nordone, Paul, Hu, Rong, Sullivan, Leah, Galambos, Eric, Fitzpatrick, Vincent, Healy, Laura, Bass, Michael, Cosenza, Mary, Afshari, Cynthia

Journal:

Toxicologic Pathology

Year:

2005

Language:

english

File:

PDF, 2.71 MB

english, 2005

37

SPIE Proceedings [SPIE International Symposium on Biomedical Optics - San Jose, CA (Saturday 19 January 2002)] Functional Monitoring and Drug-Tissue Interaction - Gene expression pattern recognition algorithm inferences to classify samples exposed to chemical agents

Bushel, Pierre R., Bennett, Lee, Hamadeh, Hisham, Green, James, Ableson, Alan, Misener, Steve, Paules, Richard, Afshari, Cynthia, Kessler, Manfred D., Mueller, Gerhard J.

Year:

2002

Language:

english

File:

PDF, 258 KB

english, 2002

38

Toxicogenomics (Principles and Applications) || Real-Time and Quantitative PCR

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 112 KB

english, 2004

39

Toxicogenomics (Principles and Applications) || Databases for Toxicogenomics

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 126 KB

english, 2004

40

Alterations in apoptotic signaling in human idiopathic cardiomyopathic hearts in failure

Steenbergen, Charles, Afshari, Cynthia A., Petranka, John G., Collins, Jennifer, Martin, Karla, Bennett, Lee, Haugen, Astrid, Bushel, Pierre, Murphy, Elizabeth

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2003

Language:

english

File:

PDF, 558 KB

english, 2003

41

Toxicogenomics (Principles and Applications) || Analytical Proteomics Approaches to Analysis of Protein Modifications: Tools for Studying Proteome-Environment Interactions

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 151 KB

english, 2004

42

Toxicogenomics (Principles and Applications) || Statistics for Toxicogenomics

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 546 KB

english, 2004

43

Toxicogenomics (Principles and Applications) || Scanners

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 275 KB

english, 2004

44

Toxicogenomics (Principles and Applications) || The Use of a Compendium of Expression Profiles for Mechanism of Toxicity Predictions

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 200 KB

english, 2004

45

Toxicogenomics (Principles and Applications) || Introduction to Metabolomics and Metabolic Profiling

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 465 KB

english, 2004

46

Toxicogenomics (Principles and Applications) || Introduction to High-Throughput Protein Expression

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 252 KB

english, 2004

47

Toxicogenomics (Principles and Applications) || General Toxicology

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 243 KB

english, 2004

48

Toxicogenomics (Principles and Applications) || Introduction to Relationships between Toxicology and Gene Expression

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

49

Toxicogenomics (Principles and Applications) || Microarray Manufacture

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 272 KB

english, 2004

50

Toxicogenomics (Principles and Applications) || Confounding Variables and Data Interpretation

Hamadeh, Hisham K., Afshari, Cynthia A.

Year:

2004

Language:

english

File:

PDF, 334 KB

english, 2004